What is AMNIOGRAFT®?
  How do you know which side of AMNIOGRAFT® is sticky?
  What size AMNIOGRAFT® should be used?
  Can AMNIOGRAFT ® be cut for use on multiple patients?



What is AMNIOGRAFT®?

AMNIOGRAFT® is Bio-Tissue’s registered trademark name for processed and cryopreserved human amniotic membrane. AMNIOGRAFT® has therapeutic actions including anti-inflammation, anti-scarring, anti-angiogenesis, and pain reduction. It supports epithelial healing and serves as a physical barrier for the ocular surface against the external environment. AMNIOGRAFT®, processed under Bio-Tissue’s patented technology, was classified as a tissue product by the US Food and Drug Administration (FDA) in 2001. The efficacy of transplanting cryopreserved AMNIOGRAFT®, is supported by hundreds of publications for ocular surface reconstruction dating back as far as 1997. Click here to see a literature summary


How do you know which side of AMNIOGRAFT® is sticky and which side goes on the eye surface?

AMNIOGRAFT® is manufactured with the stromal (sticky) side of the graft attached to white nitrocellulose filter paper.

If orientation is questionable after detaching the membrane from the paper, use a dry Weckcel or surgical applicator to check. Weckcel will only adhere to the sticky (stromal) side, but not the non-sticky (basement membrane) side. For most procedure, AMINOGRAFT® should be secured on the ocular surface with the stromal, sticky side in contact with the defect.


What size AMNIOGRAFT® should be used?

Four sizes of AMNIOGRAFT® are available:

  Cat # AG-1510, 1.5 x 1.0 cm (Size D)
  Cat # AG-2015, 2.0 x 1.5 cm (Size B)		   Cat # AG-2520, 2.5 x 2.0 cm (Size A)
  Cat # AG-3535, 3.5 x 3.5 cm (Size C)

It is recommended that the size to be ordered is 0.5 cm to 1.0 cm larger than the surgical site it is intended to cover. The following can be used as a size ordering guideline:

Indication Recommended Size
Acute Chemical Burn Two AG-3535 (size C)
Band Keratopathy AG-2520 (size A)
Bullous Keratopathy AG-2520 (size A)
Conjunctivochalasis – Focal AG-2015 (size B)
Conjunctivochalasis – Inferior Bulbar AG-2520 (size A)
Conjunctivochalasis – 360 AG-3535 (size C)
Corneal Descemetocele & Perferation AG-2015 (size B)
Corneal Epithelial Defect AG-2015 (size B)
Corneal Ulcer AG-2520 (size A)
Pinguecula, Small Tumors/Lesions AG-1510 (size D)
Pterygium AG-2015 (size B)
Pterygium – Double headed AG-3535 (size C)
Symblepharon – Focal AG-2015 (size B)
Symblepharon – Both lids Two AG-3535 (size C)
Symblepharon – Single lid AG-3535 (size C)

 

Can AMINOGRAFT® be cut for use on multiple patients?
AMNIOGRAFT ® is for SINGLE USE ONLY to comply with the FDA's GTP requirements for tracking the donor tissue to the recipient by using a distinct identification code for each transplanted tissue product.