General Tissue Storage Information

Bio-Tissue® products (PROKERA®, AmnioGraft®, & AmnioGuard®) are shipped in a temperature-controlled container and can be kept in the shipping container until the marked expiration date/time. Once removed from the shipping container, the products should be stored in a refrigerator or freezer according to the following guidelines:

Usage after receipt of Tissue/Device:

 Storage Temperature:

Acceptable Storage Location:

Storage Time:

Few hours after package arrival

Below 21°C
(69.8°F)

Unopened Insulated Shipping Container

Within the expiration date printed on the outer shipping box.

Within 3 months of receipt (no freezer available)

1°C to 10°C (33.8°F to 50°F)

Standard Refrigerator

Within 3 months of placing in the refrigerator or until expiration date printed on outer packaging, whichever comes first.

Within 1 year of receipt

-49°C
to 0°C (-56.2°F to 32°F)

Standard Freezer

(home or general use)

Within 1 year of placing in the freezer or until expiration date printed on the outer packaging, whichever comes first.

Long term storage

 -85°C to -50°C (-121°F to -58°F)

-80°C Freezer

Until expiration date printed on the outer product packaging (shelf-life is 2 years from date of manufacture).

Refer to Bio-Tissue’s Amniotic Membrane individual Product Inserts for more details.