Bio-Tissue® Proprietary CryoTek® Cryopreservation Process

  • The CryoTek® Method retains both the:
    • Integrity of the tissue structure and
    • Key active ECM and healing components
  • Cryopreservation amniotic membrane is safe and effective with over 175,000 human transplantations

Key Cryopreserved Amniotic Membrane Components

Extracellular matrix (ECM) components found in cryopreserved amniotic membrane regulate and promote regenerative tissue processes.1,2,3

Direct inhibition of pro-inflammatory cells
  • PTX 3 (HC-HA Complex)
  • Heavy chain hyaluronic acid (HC-HA)
  • Proteoglycans
  • Growth factors
  • Collagens (types I, III, IV, V and VI)
  • Fibronectin
  • Laminin

HC-HA/PTX3 Complex
Promotes Regenerative Healing

These components found uniquely in the cryopreserved amniotic membrane provide critical biologic and healing therapeutic actions:

  • Anti-inflammatory
  • Promotes limbal stem cell expansion
  • Promotes cellular migration
  • Expedites recovery
  • Suppresses pain


Click here to view Sources.