Bio-Tissue® Introduces Cliradex® Complete 

Advanced Lid Hygiene Kit

New Addition to Cliradex® Product Line for Management of Lid Margin Diseases

Doral, FL – September 1, 2014 – Bio-Tissue, Inc., the industry leader in regenerative tissue therapies and ocular hygiene products for lid margin and ocular surface diseases, today announced the launch of Cliradex® Complete Advanced Lid Hygiene Kit. Cliradex® Complete is the newest
addition to the company’s Cliradex® product line that isolates 4-Terpineol, the most important ingredient in tea tree oil, which is scientifically proven to help manage symptoms of lid margin diseases, including blepharitis, meibomian gland dysfunction (MGD), rosacea, dry eye and demodex. 

“Eye-care professionals have been looking for consistent and effective in-office management of moderate to severe cases of lid margin diseases (LMD) such as blepharitis and demodex,” said Brandon Ayres, M.D., Wills Eye Institute. “In my practice, I want to relieve discomfort and provide therapy for patients suffering from LMD. By isolating 4-Terpineol, which is scientifically proven to help manage symptoms of LMD, Cliradex® Complete provides a comprehensive and easy-to-use ocular hygiene solution that delivers improved ocular health.”  Cliradex® Complete Advanced Lid Hygiene Kit is a professional, comprehensive lid hygiene protocol featuring a formulation gel called Cliradex® Advanced Care that includes a stronger concentration of 4-Terpineol for in-office application by a doctor or trained technician. This new formulation also contains ingredients for easy removal of lid margin debris and make up.  The kit comes with a dual-sided applicator, doctor and patient materials, and a carton of Cliradex® lid wipes for patients to use at home for management of their symptoms.  This new addition to the Cliradex® product line is used for moderate to severe cases of lid margin diseases, while the current Cliradex® lid wipes can be used by patients at home for mild to moderate cases.  

Cliradex® products are natural, preservative-free lid, lash and facial cleansers, and are the only commercially-available products that isolate 4-Terpineol. “Bio-Tissue® is committed to continuing to innovate and develop products that have a positive impact on eye care and patients’ quality of life,” said Dr. Scheffer Tseng, MD, PhD, Bio-Tissue, Inc. Chairman and Chief Scientific Officer. “Through ongoing evidence-based research, we have developed Cliradex® Complete for doctors to use in office to help them improve clinical outcomes and manage symptoms of lid margin diseases.” 

About Bio-Tissue

Bio-Tissue, Inc., a subsidiary of TissueTech, is a privately held ophthalmic biotechnology company that develops innovative wound healing and hygiene solutions for the prevention and treatment of ocular surface diseases and disorders. Bio-Tissue provides a comprehensive line of FDA-cleared cryopreserved amniotic membrane ocular wound healing products, including AmnioGraft® , a biologic ocular transplantation graft; AmnioGuard®, a biologic glaucoma shunt tube graft; and the PROKERA® family of biologic corneal bandage devices. These products incorporate human amniotic membrane processed with the Company’s proprietary CryoTek® method that ensures the tissue retains its full biologic activity to reduce inflammation, promote healing, minimize corneal scarring and pain, and inhibit the angiogenic process. Bio-Tissue also developed and markets the Cliradex® line of products, natural lid, lash and facial cleansers with isolated 4-Terpineol, the active component of tea tree oil (TTO), for the management of symptoms in ocular diseases such as blepharitis, demodex, and rosacea. For more information, visit