< PROKERA® Biologic Corneal Bandage to Promote Regenerative Healing


PROKERA® biologic corneal bandage devices are used by eye doctors around the world to heal and treat ocular conditions such as keratitis, moderate to severe dry eye disease, recurrent corneal erosions, filamentary keratitis, persistent epithelial defects, neurotrophic corneas, herpetic ulcers, and many other ocular surface diseases such as chemical burns and Stevens-Johnson syndrome. The PROKERA family of products – PROKERA Slim, PROKERA, PROKERA Clear and PROKERA Plus reduce inflammation, prevents scarring and simultaneously promote regenerative healing of the ocular surface.

Natural, Therapeutic Healing

The amniotic membrane tissue in PROKERA products, which is preserved using the Company’s proprietary CRYOTEK® processing method to ensure the tissue retains its full biologic activity, has natural properties that help damaged eye surfaces heal. PROKERA products promote faster and more effective healing of the cornea with less inflammation and scarring, leading to improved clinical outcomes with better vision.

The Healing Process

PROKERA biologic corneal bandage devices are safe and effective with no risk of intraocular pressure (IOP) spikes or delayed healing that can be found in topical steroids. PROKERA products can be inserted in the doctor’s office, or may be inserted in a surgical or hospital setting in conjunction with other procedures.

PROKERA products can also be used in combination with topical agents.

PROKERA products reduce inflammation, scarring and promote healing of the ocular surface. Whether managing disease, trauma, or post-operative care, healing of the ocular surface is of paramount concern because it directly affects your patient’s comfort and appearance, and most importantly their vision.

Close up of eye

See how doctors around the country are using PROKERA®

as part of their treatment strategy:



– acts as a symblepharon ring to maintain orbital space for cases where prevention of closure or adhesion is a concern.

SKU: PK-16

– contains a double layer of CRYOTEK amniotic membrane tissue and provides extra therapeutic benefit.


– utilizes our ComfortRING technology for a lower profile device that contours to the ocular surface.


– features a 6mm Clear-View™ aperture to provide the patient with some visual acuity during treatment.


For packaging and storage information, click here.

Cutting-edge technology at the forefront of Bio-Tissue!

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How to Use

Preparing PROKERA® for Use

  • Remove PROKERA® from inner pouch
  • Rinse PROKERA® thoroughly with sterile saline solution to prevent potential stinging from preservation media
  • Patient may experience a temporary foreign body sensation upon insertion


PROKERA® Insertion

Prokera Insertion

Dr. Stephen Kimmell on Dropless Dry Eye Protocol

Dr. Stephen Kimmell, an Optometrist at the Cataract and Laser Institute in Indianapolis, has been practicing for 14 years and his specialties include advanced medical and peri-surgical care including surgical co-management for cataracts and the diagnosis and treatment of ocular diseases including macular degeneration, glaucoma and diabetic retinopathy, and dry eye disease among others. He has created his very own Dropless Dry Eye Protocol using PROKERA.

Prokera Insertion and Removal Demonstration Video

PROKERA® and Patient Management

ProkeraA tape-tarsorrhaphy (as needed) over the lid crease, narrows the eye opening, keeps PROKERA® centered & minimizes discomfort. Exposure may also cause undesirable thinning of the amniotic membrane tissue.

Follow-up Care

  • PROKERA® Membrane dissolves as healing occurs
  • Fluorescein may be used directly with PROKERA® in place to check healing
  • Intraocular pressure can be measured directly via Tonopen(R/TM)

PROKERA® Removal

Prokera Removal


Clinical Case Management

“Neel Desai, MD, discusses the use of bypassing steroids in favor of the anti-inflammatory,
anti-scarring properties in the biologic corneal bandage that restores the ocular surface without compromising the epithelial healing process.”

Neel Desai, MD

“Robert Mack, MD, discusses a new treatment option for recurrent corneal erosion, a common ocular disorder. PROKERA® can be used to restore corneal integrity, regain epithelial attachments, and prevent recurrence.”

Robert Mack, MD

“W. Barry Lee, MD recounts how a herpes simplex infection required a corneal transplant which healed in a few short days, instead of the expected weeks, through the use of a biologic corneal bandage.”

W. Barry Lee

Find Your Wow Moment



We asked key opinion leaders at the 2019 ASCRS, AOA and AAO Meetings about their experience with PROKERA® and AmnioGraft®. Check out their “Wow Moments” below!

Check out this page for more Wow Moments!

Request For More Information

Learn more about how PROKERA products are used by ophthalmologists and optometrists to control inflammation and promote improved outcomes for these patients suffering from various ocular diseases.

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